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Serology test is a simple, convenient and relatively cost-effective test for the detection of antibodies specific to Helicobacter Pylori in human serum, plasma or whole blood. It is often used for screening for Helicobacter Pylori infection. However, these tests are seldom be used to diagnose active infection or follow-up of eradication because of its relatively low accuracy. Unlike upper gastrointestinal endoscopy or urea breath test, fasting is not needed prior serology test.